Solanum anomalum Leaf Extract and Fractions Attenuate Oxidative Stress and Liver Injuries in Alloxan-Induced Diabetic Rats

The leaf of Solanum anomalum used in ethnomedicine for the treatment various ailments such as diabetes was evaluated antioxidative stress and hepatoprotective potentials against hepatic injuries alloxan-induced diabetic rats. Antioxidative activities extract fractions (70-210 mg/kg) were assessed by determining oxidative markers levels, liver function indices histopathological study livers treated caused significant (p<0.05 – 0.001) increases levels (SOD, CAT, GPx, GSH) extract/fractions reduction enzymes (ALT, AST ALP), total direct bilirubin. Histology revealed absence or reductions pathological features rats compared to untreated results show that S. has which may be due antioxidant their phytochemical constituents.